{"id":139623,"date":"2021-10-14T10:14:16","date_gmt":"2021-10-14T14:14:16","guid":{"rendered":"https:\/\/antiguanewsroom.com\/?p=139623"},"modified":"2021-10-14T15:00:12","modified_gmt":"2021-10-14T19:00:12","slug":"moderna-or-pfizer-booster-works-better-for-people-vaccinated-with-jj-study","status":"publish","type":"post","link":"https:\/\/antiguanewsroom.com\/moderna-or-pfizer-booster-works-better-for-people-vaccinated-with-jj-study\/","title":{"rendered":"Moderna or Pfizer booster works better for people vaccinated with J&J \u2013 study"},"content":{"rendered":"
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WASHINGTON,\u00a0United States\u00a0(AFP)\u2014 People who received Johnson & Johnson\u2019s COVID-19 vaccine may benefit from a booster dose of Pfizer or Moderna, preliminary results of a US study published Wednesday showed.<\/p>

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The study, funded by the National Institutes of Health (NIH), was eagerly awaited in the United States because it looked at the possibility of \u201cmixing\u201d vaccines \u2014 using a different vaccine than the initial doses for the booster shot \u2014 which is not currently allowed in the country.<\/p>\n

The study was conducted on 458 adults who had been vaccinated with one of three US-approved brands (Pfizer, Moderna or J&J) for at least 12 weeks.<\/p>

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These three groups were each divided into three new groups to receive one of the available vaccines as a booster. The nine groups consisted of about 50 people each.<\/p>

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Researchers then analyzed antibody levels 15 days after the booster shot.<\/p>\n

For people originally inoculated with J&J, antibody levels were four times higher after a J&J booster, 35 times higher after a Pfizer booster and 76 times higher after a Moderna booster.<\/p>

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And antibody levels for those who had originally received Moderna shots were higher \u201cirrespective of the booster vaccine administered,\u201d when compared with those who had initially received Pfizer or J&J, the study said.<\/p>\n

Additionally, \u201cno safety concerns were identified\u201d after booster doses were administered, it found.<\/p>

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The study, which has not yet been peer-reviewed, has several limitations, however.<\/p>

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The number of participants was small, and the immune response could evolve over time, beyond the 15 days observed during the study.<\/p>\n

\u201cImportant not to get too carried away with the findings,\u201d tweeted Peter Hotez, a professor at Baylor College of Medicine.<\/p>\n

Results from trials on a second J&J booster shot conducted by the company itself were \u201cimpressive,\u201d he said.<\/p>\n

The NIH study should fuel discussions by a US Food and Drug Administration (FDA) expert committee, which is scheduled to consider applications for a booster dose from Moderna and J&J on Thursday and Friday, respectively.<\/p>\n

A booster from Pfizer has already been approved in the United States for certain populations, such as people aged 65 or older, adults with high-risk medical conditions and those in jobs where they are frequently exposed to the coronavirus.<\/p>\n

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